Biscuits shortstop Hak-Ju Lee's first-inning bunt single extended his hitting streak to a team record-tying 20 games in Monday's 3-1 loss to the Jackson Generals.
Ralph Henriquez and Chih-Hsien Chiang both homered for Jackson in the rubber game of a three-game series.
Henriquez's fifth-inning homer off Biscuits starter Matt Buschmann snapped a 1-1 tie and Chiang made it a two-run game in the ninth off reliever Kirby Yates.
Buschmann threw seven innings, giving up one earned run on five hits. Rich Poythress singled and scored an unearned run in the second for Jackson.
Tyler Bortnick doubled home Omar Luna in the first inning for the Biscuits, who stranded 10 runners in the first four innings. They left three on in the ninth.